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Review
. 2003;5(5):235-8.
doi: 10.1186/ar991. Epub 2003 Aug 8.

Current state of cartilage tissue engineering

Richard Tuli  1 , Wan-Ju Li, Rocky S Tuan
Affiliations
Review

Current state of cartilage tissue engineering

Richard Tuli et al. Arthritis Res Ther. 2003.

Abstract

Damage to cartilage is of great clinical consequence given the tissue's limited intrinsic potential for healing. Current treatments for cartilage repair are less than satisfactory, and rarely restore full function or return the tissue to its native normal state. The rapidly emerging field of tissue engineering holds great promise for the generation of functional cartilage tissue substitutes. The general approach involves a biocompatible, structurally and mechanically sound scaffold, with an appropriate cell source, which is loaded with bioactive molecules that promote cellular differentiation and/or maturation. This review highlights aspects of current progress in cartilage tissue engineering.

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