Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2003 Aug;19(2):159-63.
doi: 10.1016/s1074-7613(03)00211-5.

Molecular phylogeny within type I cytokines and their cognate receptors

Jean-Louis Boulay  1 , John J O'Shea, William E Paul
Affiliations
Free article
Review

Molecular phylogeny within type I cytokines and their cognate receptors

Jean-Louis Boulay et al. Immunity. 2003 Aug.
Free article

Abstract

Type I helical cytokines are ligands for receptors structurally related by a common sequence signature. Here we analyze the 27 ligands and 34 human type I cytokine receptor encoded by the human genome. We compare these to ligands and receptors found in mouse and insects. We describe their structural relatedness to one another and discuss the evolution of these gene families.

PubMed Disclaimer

LinkOut - more resources