[Cytomorphological and metabolic changes in the adrenal glands of rats exposed to coal and rock dust and during exercise]

Abstract

Cytomorphological and cytochemical studies were used to examine 28 experimental non-inbred male rats that had been intratracheally exposed to 50 mg of coal rock dust (CRD) and had concurrently exercises (running) for 2 hours 5 times a week during a 3-month experiment. Toxic and physical factors were found to adversely affect the functional status of the sympathoadrenal systems of adrenal cortical cells (ACC). The most significant impairments of cytomorphological and metabolic changes were observed in ACC under the combined effects of CRD and during exercise.