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. 2003 Aug 8;91(6):068102.
doi: 10.1103/PhysRevLett.91.068102. Epub 2003 Aug 8.

Inability of Lyapunov exponents to predict epileptic seizures

Ying-Cheng Lai  1 , Mary Ann F Harrison, Mark G Frei, Ivan Osorio
Affiliations

Inability of Lyapunov exponents to predict epileptic seizures

Ying-Cheng Lai et al. Phys Rev Lett. .

Abstract

It has been claimed that Lyapunov exponents computed from electroencephalogram or electrocorticogram (ECoG) time series are useful for early prediction of epileptic seizures. We show, by utilizing a paradigmatic chaotic system, that there are two major obstacles that can fundamentally hinder the predictive power of Lyapunov exponents computed from time series: finite-time statistical fluctuations and noise. A case study with an ECoG signal recorded from a patient with epilepsy is presented.

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