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Review
. 2003 Sep;5(11):1023-7.
doi: 10.1016/s1286-4579(03)00187-4.

Gene transcription in HIV infection

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Free article
Review

Gene transcription in HIV infection

Yuntao Wu et al. Microbes Infect. 2003 Sep.
Free article

Abstract

Transcription from the HIV genome is regulated by the 5' long-terminal-repeat viral promoter as well as regulatory proteins, especially Tat and Rev. Both the promoter activity and the function of regulatory proteins require the activity of cellular components, thus the virus remains highly dependent on the metabolic state of the cell. HIV also possesses the unusual capacity to transcribe from non-integrated DNA.

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