Trials in neuropathic diabetic foot ulceration: time for a paradigm shift?

Editorial

Andrew J M Boulton et al. Diabetes Care. 2003 Sep.

. 2003 Sep;26(9):2689-90.

doi: 10.2337/diacare.26.9.2689.

No abstract available

Comment in

Off-loading in trials in neuropathic diabetic foot ulceration: no, it's not time for a paradigm shift.
Jeffcoate WJ, Game FL, Price PE. Jeffcoate WJ, et al. Diabetes Care. 2004 Feb;27(2):635-6; author reply 636-7. doi: 10.2337/diacare.27.2.635. Diabetes Care. 2004. PMID: 14747271 No abstract available.

Effect of dalteparin on healing of chronic foot ulcers in diabetic patients with peripheral arterial occlusive disease: a prospective, randomized, double-blind, placebo-controlled study.
Kalani M, Apelqvist J, Blombäck M, Brismar K, Eliasson B, Eriksson JW, Fagrell B, Hamsten A, Torffvit O, Jörneskog G. Kalani M, et al. Diabetes Care. 2003 Sep;26(9):2575-80. doi: 10.2337/diacare.26.9.2575. Diabetes Care. 2003. PMID: 12941721 Clinical Trial.
Activity patterns of patients with diabetic foot ulceration: patients with active ulceration may not adhere to a standard pressure off-loading regimen.
Armstrong DG, Lavery LA, Kimbriel HR, Nixon BP, Boulton AJ. Armstrong DG, et al. Diabetes Care. 2003 Sep;26(9):2595-7. doi: 10.2337/diacare.26.9.2595. Diabetes Care. 2003. PMID: 12941724