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Review
. 2003 Aug;14(4):407-13.
doi: 10.1016/s0958-1669(03)00097-1.

Combined metal catalysis and biocatalysis for an efficient deracemization process

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Review

Combined metal catalysis and biocatalysis for an efficient deracemization process

Oscar Pàmies et al. Curr Opin Biotechnol. 2003 Aug.

Abstract

Driven by the demand to enhance the economic balance of chemical processes, the transformation of a racemate into a single stereoisomer (the deracemization process) is one of the most important areas of research. The recent development of the combined use of enzyme and metal catalysis has led to efficient deracemization processes. Dynamic kinetic resolution and cyclic deracemization processes have shown particular promise in this area.

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