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Comment
. 2003 Aug;92(8):888-9.

Postnatal dexamethasone: what is the real cost-benefit ratio?

H L Halliday  1
Affiliations
  • PMID: 12948061
Comment

Postnatal dexamethasone: what is the real cost-benefit ratio?

H L Halliday. Acta Paediatr. 2003 Aug.

Abstract

Postnatal corticosteroids given early after birth reduce the risk of chronic lung disease in preterm infants but are associated with an approximate doubling of the risk of adverse neurosensory outcomes. Corticosteroids given after 7-10 d of age appear not to have these increased risks of neurosensory sequelae and reduce time on the ventilator.

Conclusion: Further research is needed to determine the lowest dose of corticosteroid that will improve lung function and minimize risks to the developing brain.

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