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. 1992 Nov 21;159(2):199-214.
doi: 10.1016/s0022-5193(05)80702-7.

On the origin of the transfer RNA molecule

M Di Giulio  1
Affiliations

On the origin of the transfer RNA molecule

M Di Giulio. J Theor Biol. .

Abstract

Data and arguments are given in favour of the hypothesis that the primitive tRNA molecule may have originated from a direct duplication event involving one of the two halves of the tRNA molecule. It seems that a molecule capable of assuming a hairpin structure was involved as a precursor in this duplication. The two halves of the present tRNAs could, therefore, be considered as paralogous.

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