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Review
. 2003 Aug;13(4):513-8.
doi: 10.1016/s0959-440x(03)00104-0.

Designing proteins for therapeutic applications

Greg A Lazar  1 , Shannon A Marshall, Joseph J Plecs, Stephen L Mayo, John R Desjarlais
Affiliations
Review

Designing proteins for therapeutic applications

Greg A Lazar et al. Curr Opin Struct Biol. 2003 Aug.

Abstract

Protein design is becoming an increasingly useful tool for optimizing protein drugs and creating novel biotherapeutics. Recent progress includes the engineering of monoclonal antibodies, cytokines, enzymes and viral fusion inhibitors.

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