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. 2003 Jan:135 Suppl 7:14-6.
doi: 10.1023/a:1024793621810.

Effects of phenazepam in ultralow doses on bioelectric activity of the brain and behavior of rats in various models of anxiety

T A Voronina  1 , G M Molodavkin, L I Chernyavskaya, S B Seredenin, E B Burlakova
Affiliations

Effects of phenazepam in ultralow doses on bioelectric activity of the brain and behavior of rats in various models of anxiety

T A Voronina et al. Bull Exp Biol Med. 2003 Jan.

Abstract

Phenazepam in ultralow doses produced an anxiolytic effect on male outbred albino rats in the conflict situation and elevated plus-maze models and inhibited theta-activity in EEG, which is typical of tranquilizers. As differentiated from standard doses, phenazepam in this concentration did not affect other frequency bands. Our results suggest that phenazepam in ultralow doses acts as the anxioselective tranquilizer.

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