Application of three-dimensional (3D) models of G protein-coupled receptors (GPCRs) to drug discovery

Comment

Didier Rognan. Curr Opin Drug Discov Devel. 2003 Jul.

. 2003 Jul;6(4):434.

No abstract available

Comment on

Modeling the 3D structure of GPCRs: advances and application to drug discovery.
Becker OM, Shacham S, Marantz Y, Noiman S. Becker OM, et al. Curr Opin Drug Discov Devel. 2003 May;6(3):353-61. Curr Opin Drug Discov Devel. 2003. PMID: 12833668 Review.

Modeling the 3D structure of GPCRs: advances and application to drug discovery.
Becker OM, Shacham S, Marantz Y, Noiman S. Becker OM, et al. Curr Opin Drug Discov Devel. 2003 May;6(3):353-61. Curr Opin Drug Discov Devel. 2003. PMID: 12833668 Review.
Computer modelling of G protein-coupled receptors: promises and drawbacks.
Maigret B. Maigret B. J Pharm Belg. 1997 Mar-Apr;52(2):102. J Pharm Belg. 1997. PMID: 9193133 No abstract available.
GPCR-GIP networks: a first step in the discovery of new therapeutic drugs?
Bockaert J, Dumuis A, Fagni L, Marin P. Bockaert J, et al. Curr Opin Drug Discov Devel. 2004 Sep;7(5):649-57. Curr Opin Drug Discov Devel. 2004. PMID: 15503867 Review.
Alignment-free classification of G-protein-coupled receptors using self-organizing maps.
Otaki JM, Mori A, Itoh Y, Nakayama T, Yamamoto H. Otaki JM, et al. J Chem Inf Model. 2006 May-Jun;46(3):1479-90. doi: 10.1021/ci050382y. J Chem Inf Model. 2006. PMID: 16711767
PREDICT modeling and in-silico screening for G-protein coupled receptors.
Shacham S, Marantz Y, Bar-Haim S, Kalid O, Warshaviak D, Avisar N, Inbal B, Heifetz A, Fichman M, Topf M, Naor Z, Noiman S, Becker OM. Shacham S, et al. Proteins. 2004 Oct 1;57(1):51-86. doi: 10.1002/prot.20195. Proteins. 2004. PMID: 15326594