Viral therapy for glioblastoma
- PMID: 12952302
- DOI: 10.1097/00130404-200305000-00005
Viral therapy for glioblastoma
Abstract
Malignant gliomas remain amongst the most difficult cancer to treat. Viral-based gene therapies have been employed for the last decade in preclinical and clinical modes as a novel treatment modality. In this review, such therapies are summarized. The overwhelming majority of clinical studies point one to conclude that methodologies that will increase tumor infection/transduction will lead to enhanced therapeutic results.
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