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Review
. 2003 May-Jun;9(3):167-79.
doi: 10.1097/00130404-200305000-00005.

Viral therapy for glioblastoma

E Antonio Chiocca  1 , Manish Aghi, Giulia Fulci
Affiliations
Review

Viral therapy for glioblastoma

E Antonio Chiocca et al. Cancer J. 2003 May-Jun.

Abstract

Malignant gliomas remain amongst the most difficult cancer to treat. Viral-based gene therapies have been employed for the last decade in preclinical and clinical modes as a novel treatment modality. In this review, such therapies are summarized. The overwhelming majority of clinical studies point one to conclude that methodologies that will increase tumor infection/transduction will lead to enhanced therapeutic results.

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