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. 2003 Sep 15;37(6):857-9.
doi: 10.1086/378587. Epub 2003 Aug 28.

Expression of lymphocytes and lymphocyte subsets in patients with severe acute respiratory syndrome

Wei Cui  1 , Ying Fan, Wei Wu, Feng Zhang, Jun-ying Wang, An-ping Ni
Affiliations

Expression of lymphocytes and lymphocyte subsets in patients with severe acute respiratory syndrome

Wei Cui et al. Clin Infect Dis. .

Abstract

In a cohort of 38 patients with severe acute respiratory syndrome (SARS), we observed leukopenia in 47% of patients, lymphopenia in 84%, and T lymphopenia in 95%. CD4(+) T lymphocyte levels were reduced in 100% of patients, CD8(+) T lymphocyte levels were reduced in 87%, B lymphocyte levels were reduced in 76%, and natural killer cell levels were reduced in 55%. Our data suggested that these patients' immune systems were impaired during the course of SARS. The absolute counts of lymphocyte subsets demonstrated a clinical significance for patients with SARS.

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Figures

Table 1
Table 1
Leukocyte and lymphocyte levels in 38 patients with severe acute respiratory syndrome and in 200 healthy control subjects.
Table 2
Table 2
Absolute counts of lymphocyte subsets in 38 patients with severe acute respiratory syndrome and in 200 healthy control subjects.
Table 3
Table 3
Percentages of lymphocyte subsets in 38 patients with severe acute respiratory syndrome and in 200 healthy control subjects.
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