Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2003 Sep 5;17(13):1985-8.
doi: 10.1097/00002030-200309050-00019.

Altered lymphocyte heat shock protein 70 expression in patients with HIV disease

Linda L Agnew  1 , Mark Kelly, Jonathan Howard, Sarangapany Jeganathan, Marijka Batterham, Rosemary A Ffrench, Julian Gold, Kenneth Watson
Affiliations

Altered lymphocyte heat shock protein 70 expression in patients with HIV disease

Linda L Agnew et al. AIDS. .

Abstract

Heat shock protein (HSP) expression in lymphocytes isolated from 20 patients with HIV disease and 15 age-matched controls was determined. Fold increases in lymphocyte hsp70 expression after heat shock were 4.52 +/- 2.97 in HIV-positive individuals compared with 2.60 +/- 1.29 for HIV-negative controls (P= 0.001). Given clear roles for HSP in the cross-presentation of antigens, alpha-defensin internalization and pro-inflammatory cytokine production, a further investigation of HSP in HIV patients is merited.

PubMed Disclaimer

Publication types

Substances