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Review
. 2003 Aug;20(4):382-91.
doi: 10.1039/b208815k.

Natural products--a simple model to explain chemical diversity

Richard D Firn  1 , Clive G Jones
Affiliations
Review

Natural products--a simple model to explain chemical diversity

Richard D Firn et al. Nat Prod Rep. 2003 Aug.

Abstract

A simple evolutionary model is presented which explains why organisms produce so many natural products, why so many have low biological activity, why enzymes involved in natural product synthesis have the properties they do and why natural product metabolism is shaped as it is.

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