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. 1992 Dec;30(11-12):591-601.

Antithrombin III (AT3) polymorphism in the marsupial Monodelphis domestica: identification and genetics

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  • PMID: 1296573

Antithrombin III (AT3) polymorphism in the marsupial Monodelphis domestica: identification and genetics

K Bell et al. Biochem Genet. 1992 Dec.

Abstract

Antithrombin III polymorphism was observed in the gray short-tailed opossum, Monodelphis domestica, by either one-dimensional polyacrylamide gel electrophoresis (PAGE; pH 7.9), two-dimensional PAGE (agarose, pH 5.4; 12% T, pH 7.9), or isoelectric focusing (pH 4.2-4.9) followed by immunoblotting with rabbit antiserum to human antithrombin III. Family studies demonstrated an inheritance of three codominant autosomal alleles, AT3A, AT3B, and AT3C, and a population study revealed frequencies of 0.70, 0.10, and 0.20, respectively.

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