doi: 10.1021/ol0353060.
Bridgehead arylation: a direct route to advanced intermediates for the synthesis of C-20 diterpene alkaloids
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- PMID: 12967309
- DOI: 10.1021/ol0353060
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Bridgehead arylation: a direct route to advanced intermediates for the synthesis of C-20 diterpene alkaloids
Org Lett.
.
Abstract
[reaction: see text] Rapid access to the ABCE ring system of the C(20) diterpene alkaloids was achieved by silver(I)-promoted intramolecular Friedel-Crafts arylation of a functional group-specific 5-bromo-3-azabicyclo[3.3.1]nonane derivative.
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