Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2003 Sep 18;5(19):3499-502.
doi: 10.1021/ol0353060.

Bridgehead arylation: a direct route to advanced intermediates for the synthesis of C-20 diterpene alkaloids

Craig M Williams  1 , Lewis N Mander
Affiliations

Bridgehead arylation: a direct route to advanced intermediates for the synthesis of C-20 diterpene alkaloids

Craig M Williams et al. Org Lett. .

Abstract

[reaction: see text] Rapid access to the ABCE ring system of the C(20) diterpene alkaloids was achieved by silver(I)-promoted intramolecular Friedel-Crafts arylation of a functional group-specific 5-bromo-3-azabicyclo[3.3.1]nonane derivative.

PubMed Disclaimer

LinkOut - more resources