Pro/Con debate of activated protein C in severe sepsis
- PMID: 12973192
- DOI: 10.1097/01.CCM.0000087327.59341.18
Pro/Con debate of activated protein C in severe sepsis
Erratum in
- Crit Care Med. 2003 Dec;31(12):2816. Figen J W [corrected to Fijen J W]
Comment on
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Drotrecogin alfa (activated) (recombinant human activated protein C) for the treatment of severe sepsis.Crit Care Med. 2003 Jan;31(1 Suppl):S85-93. doi: 10.1097/00003246-200301001-00012. Crit Care Med. 2003. PMID: 12544981 Review.
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Recombinant human activated protein C in sepsis: inconsistent trial results, an unclear mechanism of action, and safety concerns resulted in labeling restrictions and the need for phase IV trials.Crit Care Med. 2003 Jan;31(1 Suppl):S94-6. doi: 10.1097/00003246-200301001-00013. Crit Care Med. 2003. PMID: 12544982 Review. No abstract available.
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