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Comment

. 2003 Aug;31(8):2249.

doi: 10.1097/01.CCM.0000087327.59341.18.

Pro/Con debate of activated protein C in severe sepsis

J C A Joore, H J van Leeuwen, J Meulenbelt, T J M Tobé, J W Fijen

PMID: 12973192
DOI: 10.1097/01.CCM.0000087327.59341.18

Comment

Pro/Con debate of activated protein C in severe sepsis

J C A Joore et al. Crit Care Med. 2003 Aug.

. 2003 Aug;31(8):2249.

doi: 10.1097/01.CCM.0000087327.59341.18.

Authors

J C A Joore, H J van Leeuwen, J Meulenbelt, T J M Tobé, J W Fijen

PMID: 12973192
DOI: 10.1097/01.CCM.0000087327.59341.18

Erratum in

Crit Care Med. 2003 Dec;31(12):2816. Figen J W [corrected to Fijen J W]

No abstract available

PubMed Disclaimer

Comment on

Drotrecogin alfa (activated) (recombinant human activated protein C) for the treatment of severe sepsis.
Bernard GR. Bernard GR. Crit Care Med. 2003 Jan;31(1 Suppl):S85-93. doi: 10.1097/00003246-200301001-00012. Crit Care Med. 2003. PMID: 12544981 Review.
Recombinant human activated protein C in sepsis: inconsistent trial results, an unclear mechanism of action, and safety concerns resulted in labeling restrictions and the need for phase IV trials.
Eichacker PQ, Natanson C. Eichacker PQ, et al. Crit Care Med. 2003 Jan;31(1 Suppl):S94-6. doi: 10.1097/00003246-200301001-00013. Crit Care Med. 2003. PMID: 12544982 Review. No abstract available.

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