Review
doi: 10.1034/j.1600-0463.2003.11107808.x.
Dendritic cells in peripheral tolerance and immunity
Affiliations
- PMID: 12974778
- DOI: 10.1034/j.1600-0463.2003.11107808.x
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Review
Dendritic cells in peripheral tolerance and immunity
APMIS.
2003 Jul-Aug.
Abstract
Dendritic cells capable of influencing immunity exist as functionally distinct subsets, T cell-tolerizing and T cell-immunizing subsets. The present paper reviews how these subsets of DCs develop, differentiate and function in vivo and in vitro at the cellular and molecular level. In particular, the role of DCs in the generation of regulatory T cells is highlighted.
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