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Review
. 2003 Jul-Aug;111(7-8):766-75.
doi: 10.1034/j.1600-0463.2003.11107808.x.

Dendritic cells in peripheral tolerance and immunity

Monika Gad  1 , Mogens Helweg Claesson, Anders Elm Pedersen
Affiliations
Review

Dendritic cells in peripheral tolerance and immunity

Monika Gad et al. APMIS. 2003 Jul-Aug.

Abstract

Dendritic cells capable of influencing immunity exist as functionally distinct subsets, T cell-tolerizing and T cell-immunizing subsets. The present paper reviews how these subsets of DCs develop, differentiate and function in vivo and in vitro at the cellular and molecular level. In particular, the role of DCs in the generation of regulatory T cells is highlighted.

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