[Incidence and characteristics of clinical and sub-clinic hyperthyroidism]
- PMID: 12975083
- PMCID: PMC7669072
- DOI: 10.1016/s0212-6567(03)79253-1
[Incidence and characteristics of clinical and sub-clinic hyperthyroidism]
Abstract
Objectives: Estimate the incidence of hyperthyroidism in the region of Lleida and compare patients with clinic and subclinic hyperthyroidism.
Design: Descriptive retrospective.
Localization: City of Lleida and the towns of the provinces of Lleida and Huesca.
Patients: 190 people diagnosed of hyperthyroidism detected from a sample of 1885 patients with different pathologies, belonging to first visits to de Service of Endocrinology of the Hospital Arnau de Vilanova, during the period from 1999 to 2000.
Main measurements: The following clinic and demographical variables related to the thyroid pathology were recorded: TSH, T(4), T(3), anti-Tg antibodies, anti-TPO antibodies, age, gender, consumption of salt with iodine and the incidence tax of hyperthyroidism.
Results: The incidence tax of hyperthyroidism in the province of Lleida was 46.2 ×10(5) people/year (95% CI, 33.5-61.0). For the 190 patients, the 85% (95% CI, 79.4-90) of them were women; the 38% (95% CI, 31%-45.2%) and the 62% (95% CI, 54.8-69) were diagnosed of clinic and subclinic hyperthyroidism respectively. The subclinic profile was characteristically for had a superior mean of age (P<.003), double of TSH level (P<.03) and half of T(4) level of (P<.001).
Conclusion: Our study shows a high incidence of hyperthyroidism, and a difference of the two hyperthyroidisms. The detection of this pathology by professionals of primary care can help to improve their therapeutic control.
Objetivos: Estimar la incidencia de hipertiroidismo en la región de Lleida y comparar a los pacientes con hipertiroidismo clínico y subclínico.
Diseño: Descriptivo retrospectivo.
Emplazamiento: Lleida ciudad y municipios de las provincias de Lleida y Huesca.
Participantes: Ciento noventa personas diagnosticadas de hipertiroidismo detectadas en un grupo de 1.885 pacientes con patologías diferentes, pertenecientes a las primeras visitas del Servicio de Endocrinología del Hospital Universitario Arnau de Vilanova en el período 1999–2000.
Mediciones principales: Se recogieron lasvariables clínicas y demográficas relacionadas con la patología tiroidea: tirotropina, tetrayodotironina libre, triyodotironina total, anticuerpos antitiroglobulina, anticuerpos antiperoxidasa, edad, sexo, ingesta de sal yodada y tasa de incidencia de hipertiroidismo.
Resultados: La tasa de incidencia dehipertiroidismo en los municipios de Lleida fue de 46,2 *105 habitantes-año (IC del 95%, 33,5-61,0). De los 190 pacientes, el 85,3% (IC del 95%, 79,4–90) fueron mujeres. El 38% (IC del 95%, 31–45,2%) y el 62% (IC del 95%, 54,8–69) fueron diagnosticados de hipertiroidismo clínico y subclínico, respectivamente.El perfil de los pacientes con hipertiroidismo subclínico se caracterizó por: media de edad superior (p < 0,003), un valor de tirotropina del doble (p < 0,03) y un valor de tetrayodotironina de la mitad (p < 0,001).
Conclusiones: En nuestro estudio se objetiva una alta tasa de incidencia y diferencia sentre las dos clases de hipertiroidismo. La detección de esta patología por profesionales de atención primaria puede ayudar a mejorar su control terapéutico.
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