Transcriptional repression by methylation of CpG
- PMID: 1297654
- DOI: 10.1242/jcs.1992.supplement_16.2
Transcriptional repression by methylation of CpG
Abstract
Methylated DNA in mammals is associated with transcriptional repression and nuclease resistant chromatin. In this review we discuss how these effects may be mediated by proteins that bind to methylated DNA.