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Review
. 1992:Spec No:161-4.
doi: 10.3177/jnsv.38.special_161.

Bioavailability and biological activity of L-ascorbic acid 2-O-alpha-glucoside

I Yamamoto  1 , N Muto
Affiliations
Review

Bioavailability and biological activity of L-ascorbic acid 2-O-alpha-glucoside

I Yamamoto et al. J Nutr Sci Vitaminol (Tokyo). 1992.

Abstract

AA-2G is a new stable derivative of AsA which is efficiently synthesized by regioselective transglucosylation with alpha-glucosidase and CGTase. AA-2G serves as a vitamin C supplement in experimental animals. AA-2G is easily hydrolyzed in vivo by alpha-glucosidase and also synthesized as a metabolite under some specified conditions. AA-2G stimulates collagen synthesis in cultured fibroblasts and enhances antibody production in cultured splenocytes. AA-2G which has no cytotoxicity is a promising AsA derivative for medical and nutritional uses.

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