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Case Reports
. 1992;62(4):459-64.
doi: 10.1159/000187099.

Double monoclonal cryoglobulinemia, glomerulonephritis and lymphoma

C Rollino  1 , A Dieny, F Le Marc'hadour, J C Renversez, N Pinel, D Cordonnier
Affiliations
Case Reports

Double monoclonal cryoglobulinemia, glomerulonephritis and lymphoma

C Rollino et al. Nephron. 1992.

Abstract

We present a case of monoclonal cryoglobulinemia with double monoclonal component IgA lambda-IgG lambda, without complement activation, membranoproliferative glomerulonephritis (MPGN) with deposits of IgA, IgG and lambda chains and lymphocytic IgA-lambda-chain-secreting lymphoma. This case emphasizes the possibility that double monoclonal cryoglobulins could behave differently compared to type I cryoglobulins, determining a MPGN-like type II cryoglobulins do, but without activating the complement cascade.

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