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. 1976 Mar 5;426(2):335-8.
doi: 10.1016/0005-2736(76)90342-4.

Changes in some marker enzyme activities of liver plasma membranes during regeneration after partial hepatectomy in rats

Changes in some marker enzyme activities of liver plasma membranes during regeneration after partial hepatectomy in rats

Y Masuda et al. Biochim Biophys Acta. .

Abstract

Liver plasma membranes were isolated from regenerating rat livers between 20 h and 10 days after partial hepatectomy in order to study the effect of partial hepatectomy on some membrane enzyme activities. Mg2+-ATPase (EC 3.6.1.4) activity, but not (Na+ + K+)-ATPase activity, decreased slightly at 2 days, whereas leucyl beta-naphthylamidase (EC3.4.1.1) and 5'-nucleotidase (EC3.1.3.5) activities increased considerably at 1-2 and 3-5 days, respectively. These changes were not parallel to a sharp increase in mitotic activity of liver cells which occurred at 36 h.

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