doi: 10.1192/bjp.128.2.169.
A biochemical study of short-cycle manic-depressive psychosis in mental defectives
- PMID: 130181
- DOI: 10.1192/bjp.128.2.169
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A biochemical study of short-cycle manic-depressive psychosis in mental defectives
Br J Psychiatry.
1976 Feb.
Abstract
Four mentally defective patients who were suffering from short-cycle manic-depressive psychosis were each studied under metabolic ward conditions for about six months. Weekly estimations of erythrocyte Na-K ATPase activity, ouabain sensitive potassium influx, sodium concentration, whole blood cell ATP concentration and blood haematocrit were made. The findings in each patient differed, but the erythrocyte Na-K ATPase activity, sodium and ATP concentration appeared to show cyclic changes related to, though out of phase with, the clinical state.
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