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. 1992 Jul;1(4):269-73.
doi: 10.1093/hmg/1.4.269.

Identification and characterization of a new gene in the human Xq28 region

A M van den Ouweland  1 , P Kioschis, M Verdijk, F Tamanini, D Toniolo, A Poustka, B A van Oost
Affiliations

Identification and characterization of a new gene in the human Xq28 region

A M van den Ouweland et al. Hum Mol Genet. 1992 Jul.

Abstract

A human Xqter chromosome cosmid library was screened with a mixed probe derived from porcine kidney mRNA. A new expressed gene was identified in a cosmid clone known to be part of a G6PD cosmid contig. This gene is most likely a housekeeping gene because the cDNA clone recognizes a 1 kb mRNA transcript in all cell lines and tissues tested. Hybridizing genomic DNA of several species with a cDNA probe indicated that the gene is highly conserved during evolution and that it belongs to a gene family. The genomic sequence shows a 100% homology with the recently identified QM cDNA sequence.

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