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Review
. 1992 Jun;13(6):224-30.
doi: 10.1016/0167-5699(92)90159-5.

Regulatory mechanisms in leukocyte adhesion: flexible receptors for sophisticated travelers

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Review

Regulatory mechanisms in leukocyte adhesion: flexible receptors for sophisticated travelers

R Pardi et al. Immunol Today. 1992 Jun.

Abstract

Unstimulated leukocytes spend extended periods circulating in the blood, punctuated by migration through lymphoid areas and peripheral tissues. During transit, strong cell-cell interactions control immune surveillance and specialized effector functions. The structures and mechanisms that allow this flexible adhesion and migration behavior are the subject of this review.

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