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. 1992 Feb;174(4):1414-6.
doi: 10.1128/jb.174.4.1414-1416.1992.

Isocitrate dehydrogenase kinase/phosphatase: identification of mutations which selectively inhibit phosphatase activity

T P Ikeda  1 , E Houtz, D C LaPorte
Affiliations

Isocitrate dehydrogenase kinase/phosphatase: identification of mutations which selectively inhibit phosphatase activity

T P Ikeda et al. J Bacteriol. 1992 Feb.

Abstract

Mutations in aceK, the gene encoding isocitrate dehydrogenase kinase/phosphatase, which selectively inhibit phosphatase activity have been isolated. These mutations yield amino acid substitutions within a 113-residue region of this 578-residue protein. These mutations may define a regulatory domain of this protein.

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