doi: 10.1128/JVI.66.3.1804-1808.1992.
Simian virus 40 (SV40) small t antigen inhibits SV40 DNA replication in vitro
Affiliations
- PMID: 1310784
- PMCID: PMC240946
- DOI: 10.1128/JVI.66.3.1804-1808.1992
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Simian virus 40 (SV40) small t antigen inhibits SV40 DNA replication in vitro
J Virol.
1992 Mar.
Abstract
We describe a biochemical function of simian virus 40 small t antigen, the inhibition of simian virus 40 large T antigen-mediated viral DNA replication in an in vitro replication system. Our results suggest that in this system, small t antigen prevents protein phosphatase 2A-mediated activation of large T antigen.
Comment in
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Familial malignant mesothelioma.Lancet. 2001 Nov 24;358(9295):1813-4. doi: 10.1016/S0140-6736(01)06816-7. Lancet. 2001. PMID: 11734267 No abstract available.
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