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. 1992 Mar;66(3):1804-8.
doi: 10.1128/JVI.66.3.1804-1808.1992.

Simian virus 40 (SV40) small t antigen inhibits SV40 DNA replication in vitro

M Carbone  1 , J Hauser, M P Carty, K Rundell, K Dixon, A S Levine
Affiliations

Simian virus 40 (SV40) small t antigen inhibits SV40 DNA replication in vitro

M Carbone et al. J Virol. 1992 Mar.

Abstract

We describe a biochemical function of simian virus 40 small t antigen, the inhibition of simian virus 40 large T antigen-mediated viral DNA replication in an in vitro replication system. Our results suggest that in this system, small t antigen prevents protein phosphatase 2A-mediated activation of large T antigen.

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  • Familial malignant mesothelioma.
    Saracci R, Simonato L. Saracci R, et al. Lancet. 2001 Nov 24;358(9295):1813-4. doi: 10.1016/S0140-6736(01)06816-7. Lancet. 2001. PMID: 11734267 No abstract available.

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