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Clinical Trial
. 1992 Feb;239(2):79-81.
doi: 10.1007/BF00862977.

A double-blind placebo-controlled trial of L-threonine in amyotrophic lateral sclerosis

O Blin  1 , J Pouget, G Aubrespy, C Guelton, A Crevat, G Serratrice
Affiliations
Clinical Trial

A double-blind placebo-controlled trial of L-threonine in amyotrophic lateral sclerosis

O Blin et al. J Neurol. 1992 Feb.

Abstract

Fifteen patients with the unequivocal diagnosis of amyotrophic lateral sclerosis (ALS) completed a 1-year randomized double-blind placebo-controlled trial of L-threonine (2 g daily). During the study, patients in the placebo group showed a decline in functional status consistent with the natural history of ALS, which was not statistically different from outcome in the patients in the L-threonine group.

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