Synergistic combination of azithromycin and sulfadiazine for treatment of toxoplasmosis in mice
- PMID: 1314177
- DOI: 10.1007/BF01971278
Synergistic combination of azithromycin and sulfadiazine for treatment of toxoplasmosis in mice
Abstract
Experiments were performed in vivo in a mouse model of acute toxoplasmosis to evaluate the effectiveness of the combination azithromycin/sulfadiazine. Azithromycin alone or sulfadiazine alone, at doses that did not provide any protection against death due to toxoplasmosis, were remarkably and significantly synergistic against murine toxoplasmosis when administered in combination.