Comparative Study
doi: 10.1016/0891-5849(92)90025-c.
Lacidipine: a dihydropyridine calcium antagonist with antioxidant activity
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- PMID: 1314212
- DOI: 10.1016/0891-5849(92)90025-c
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Comparative Study
Lacidipine: a dihydropyridine calcium antagonist with antioxidant activity
Free Radic Biol Med.
1992.
Abstract
Lacidipine, a new, long-acting antihypertensive dihydropyridine calcium antagonist was tested for potential antioxidant effect in a series of tests that consider specific radical species. A direct quenching of several radical species could be measured. Moreover, in biological membranes deriving from rat brain tissue, lacidipine showed an activity comparable to reference antioxidant compounds like vitamin E.
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