Association of the RTX proteins of Actinobacillus pleuropneumoniae with hemolytic, CAMP, and neutrophil-cytotoxic activities
- PMID: 1314227
- PMCID: PMC257130
- DOI: 10.1128/iai.60.5.2139-2142.1992
Association of the RTX proteins of Actinobacillus pleuropneumoniae with hemolytic, CAMP, and neutrophil-cytotoxic activities
Abstract
The immunoglobulin G from a monospecific rabbit antiserum to the 110-kDa RTX hemolysin of Actinobacillus pleuropneumoniae serotype 1 was used to determine that the related RTX proteins in isolates from serotypes 2 to 12 were also responsible for the hemolytic, CAMP, and neutrophil-cytotoxic activities produced by this bacterium. These proteins share common neutralizing epitopes.
Similar articles
-
Immunoserological comparison of 104-kilodalton proteins associated with hemolysis and cytolysis in Actinobacillus pleuropneumoniae, Actinobacillus suis, Pasteurella haemolytica, and Escherichia coli.Infect Immun. 1989 Oct;57(10):3210-3. doi: 10.1128/iai.57.10.3210-3213.1989. Infect Immun. 1989. PMID: 2674017 Free PMC article.
-
Functional and structural changes of porcine alveolar macrophages induced by sublytic doses of a heat-labile, hemolytic, cytotoxic substance produced by Actinobacillus pleuropneumoniae.Am J Vet Res. 1994 Nov;55(11):1548-57. Am J Vet Res. 1994. PMID: 7879978
-
Elucidating the role of ApxI in hemolysis and cellular damage by using a novel apxIA mutant of Actinobacillus pleuropneumoniae serotype 10.J Vet Sci. 2014;15(1):81-9. doi: 10.4142/jvs.2014.15.1.81. Epub 2013 Jun 30. J Vet Sci. 2014. PMID: 23820218 Free PMC article.
-
Virulence in Actinobacillus pleuropneumoniae and RTX toxins.Trends Microbiol. 1995 Jul;3(7):257-61. doi: 10.1016/s0966-842x(00)88939-8. Trends Microbiol. 1995. PMID: 7551637 Review.
-
Actinobacillus pleuropneumoniae: pathobiology and pathogenesis of infection.Microbes Infect. 2002 Feb;4(2):225-35. doi: 10.1016/s1286-4579(01)01534-9. Microbes Infect. 2002. PMID: 11880056 Review.
Cited by
-
Secreted proteases from Actinobacillus pleuropneumoniae serotype 1 degrade porcine gelatin, hemoglobin and immunoglobulin A.Can J Vet Res. 1994 Apr;58(2):83-6. Can J Vet Res. 1994. PMID: 8004545 Free PMC article.
-
Actinobacillus pleuropneumoniae culture supernatants interfere with killing of Pasteurella multocida by swine pulmonary alveolar macrophages.Can J Vet Res. 1993 Jul;57(3):190-7. Can J Vet Res. 1993. PMID: 8358680 Free PMC article.
-
Relatedness of Streptococcus canis from canine streptococcal toxic shock syndrome and necrotizing fasciitis.Can J Vet Res. 1999 Apr;63(2):90-5. Can J Vet Res. 1999. PMID: 10369564 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases