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Case Reports
. 1992;21(2):121-3.
doi: 10.1007/BF00241839.

Case report 714. Postirradiation osteosarcoma after radiation of metastatic skeletal lesion

B C Toorkey  1 , K K Unni, D C Dahlin
Affiliations
Case Reports

Case report 714. Postirradiation osteosarcoma after radiation of metastatic skeletal lesion

B C Toorkey et al. Skeletal Radiol. 1992.

Abstract

Two cases of postirradiation osteosarcoma are presented--one in a 76-year-old woman with breast carcinoma and subsequent osteosarcoma after radiation therapy for a metastatic lesion in the right tibia, and the other in a 16-year-old girl with hepatocellular carcinoma metastatic to the left tibia and osteosarcoma after radiation therapy to that bone. Microscopically, both cases were high-grade spindle cell lesions with osteoid production. Both patients fared poorly. This is a rare complication of radiation therapy.

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