[Histiocyte activation syndrome associated with EBV in children]
[Article in
Italian]
Affiliations
- PMID: 1314725
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[Histiocyte activation syndrome associated with EBV in children]
[Article in
Italian]
Clin Ter.
1992 Feb.
Abstract
VAHS (virus associated hemophagocytic syndrome) is a severe clinical and biological condition associated with certain menacing viral infections. It has been observed in patients with manifest immunodeficiency but also in previously apparently healthy children. Epstein-Barr virus (EBV) infection, although it is sometimes unrecognized and insidious, is one of the etiologies to be considered. Differential diagnosis with other causes of macrophage activation is a delicate task in pediatrics. Better understanding of the pathophysiology of the syndrome offers interesting therapeutic prospects.
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