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. 1954 May 1;99(5):495-503.
doi: 10.1084/jem.99.5.495.

Myocardial necrosis produced in animals by means of crystalline streptococcal proteinase

A KELLNER, T ROBERTSON

Myocardial necrosis produced in animals by means of crystalline streptococcal proteinase

A KELLNER et al. J Exp Med. .

Abstract

Focal myocardial necrosis that was often extensive was found in a high percentage of rabbits, guinea pigs, and mice given a single intravenous injection of crystalline streptococcal proteinase. The findings are discussed in relation to their possible implications for the pathogenesis of the cardiac lesions of rheumatic fever.

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