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. 1976 Feb 25;83(558):114-6.

Combined therapy with tetrabenazine and pimozide in Huntington's chorea: pilot study

A W McArthur, M Pollock, N A Smidt
  • PMID: 131917

Combined therapy with tetrabenazine and pimozide in Huntington's chorea: pilot study

A W McArthur et al. N Z Med J. .

Abstract

Current medication for Huntingtons chorea is based on compounds which affect the activity of acetylcholine and dopamine in the basal ganglia and is unsatisfactory. This report describes a small clinical trial of dopamine antagonists, tetrabenazine (Nitoman) and pimozide (Orap). Improvement was early and striking but was not maintained over the trial period of 83 weeks.

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