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. 1975:7:249-55.

Estimated glycolytic flux in infarcting heart

L H Opie, P Owen, W Lubbe
  • PMID: 131960

Estimated glycolytic flux in infarcting heart

L H Opie et al. Recent Adv Stud Cardiac Struct Metab. 1975.

Abstract

Regional ischemia results in infarction even in the presence of residual oxidative metabolism. Although glycolytic flux is relatively inhibited at the level of phosphofructokinase, glucose competes more effectively than does free fatty acid for the residual oxygen supply. Glycogen is not the major energy source until effective collateral flow is virtually zero.

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