Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1954 Dec 1;100(6):641-56.
doi: 10.1084/jem.100.6.641.

Studies on the endoplasmic reticulum. I. Its identification in cells in situ

G E PALADE, K R PORTER

Studies on the endoplasmic reticulum. I. Its identification in cells in situ

G E PALADE et al. J Exp Med. .

Abstract

A series of representative cell types including avian fibroblasts, and macrophages; rabbit mesothelia, endothelia, and nephron epithelia; and rat glandular epithelia (parotid) were studied comparatively in vitro and in situ with the electron microscope. Cells in vitro were examined in whole mounts and in sections whereas cells in situ were observed exclusively in sections. It was found that an endoplasmic reticulum similar to that previously described in cultured material is present in situ in all cell types examined. Modifications in its appearance introduced by the sectioning technique were discussed and explained. The observations showed in addition that the endoplasmic reticulum is a network of cavities which may enlarge into relatively vast, flattened vesicles here described as cisternae.

PubMed Disclaimer

References

    1. Anat Rec. 1953 Dec;117(4):685-710 - PubMed
    1. Cancer. 1952 Jul;5(4):770-86 - PubMed
    1. J Exp Med. 1945 Mar 1;81(3):233-46 - PubMed
    1. Am J Pathol. 1925 Jan;1(1):91-100.1 - PubMed
    1. Bull Johns Hopkins Hosp. 1953 Apr;92(4):257-89 - PubMed