Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1976 Apr 21;255(2):129-38.
doi: 10.1007/BF00558520.

Topical vitamin A acid in the treatment of acne vulgaris (a controlled multicenter trial)

M Gandola, G Argenziano, C Barba, R Bassi, M Binazzi, G Landi, L Levi, D Randazzo, F Serri, A P Villano
Clinical Trial

Topical vitamin A acid in the treatment of acne vulgaris (a controlled multicenter trial)

M Gandola et al. Arch Dermatol Res (1975). .

Abstract

A controlled non-blind multicenter trial was conducted in 211 acne patients to test the activity of topical retinoic acid against sulfur-resorcinol--salicylic acid and placebo. Uniform evaluation criteria were used. After 8 weeks' treatment in comparable groups of patients, retinoic acid proved to be superior to the standard and to the placebo. The difference was statistically significant. Side effects were present in a number of patients treated with the active substances and with the placebo (mainly erythema), but rarely was the treatment discontinued.

PubMed Disclaimer

References

    1. Br J Dermatol. 1974 May;90(5):553-60 - PubMed
    1. Arch Klin Exp Dermatol. 1971;239(4):390-413 - PubMed
    1. Am J Clin Nutr. 1961 Jul-Aug;9(4)Pt 2:23-6 - PubMed
    1. Schweiz Med Wochenschr. 1964 Feb 15;94:218-21 - PubMed
    1. Arch Dermatol. 1972 Aug;106(2):200-3 - PubMed