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. 1992 Sep;54(3):533-7.
doi: 10.1016/0003-4975(92)90449-e.

Prognostic significance of computed tomography in resected N2 lung cancer

I J Cybulsky  1 , L A Lanza, M B Ryan, J B Putnam Jr, M M McMurtrey, J A Roth
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Prognostic significance of computed tomography in resected N2 lung cancer

I J Cybulsky et al. Ann Thorac Surg. 1992 Sep.

Abstract

We reviewed 124 patients from 1982 to 1988 who had a resected primary non-small cell lung cancer metastatic to mediastinal (N2) lymph nodes and a preoperative assessment of the mediastinum with computed tomography of the chest. Sixty-three patients studied had computed tomographic evidence of mediastinal lymph node enlargement. In these patients the survival at 5 years was only 6.6%, compared with the 5-year survival of 13.5% in 61 patients in whom the mediastinum was normal. Plain chest roentgenography with evidence of mediastinal adenopathy did not predict a poorer outcome. In addition, patients with tumors located in the left upper lobe were found to have an improved survival. These patients had a 5-year survival of 20.8%. Tumor histology, central location of the tumor, extranodal extension, and type of resection did not result in a significant survival difference.

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