Comparative Study
doi: 10.1016/0378-1119(92)90256-o.
The DNA polymerase-encoding gene of Bacillus subtilis bacteriophage SPO1
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- PMID: 1324872
- DOI: 10.1016/0378-1119(92)90256-o
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Comparative Study
The DNA polymerase-encoding gene of Bacillus subtilis bacteriophage SPO1
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Abstract
The bacteriophage SPO1 DNA polymerase-encoding gene, which contains a self-splicing intron, has been sequenced and its amino acid (aa) sequence has been deduced. The aa sequence of SPO1 DNA polymerase shows a high degree of similarity with that of DNA polymerase I from Escherichia coli (Po1I). Alignment with the sequences of Po1I, and the phi 29 and SPO1 DNA polymerases indicate that the aa residues that have been implicated in 3'----5' exonuclease activities are conserved.
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