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. 1992 Sep 10;118(2):297-8.
doi: 10.1016/0378-1119(92)90205-4.

A mouse c-ros genomic clone: identification of a highly conserved 22-amino acid segment in the juxta-membrane domain

L Narayana  1 , L Nagarajan
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A mouse c-ros genomic clone: identification of a highly conserved 22-amino acid segment in the juxta-membrane domain

L Narayana et al. Gene. .

Abstract

The mouse c-ros protooncogene genomic sequences have been cloned; an analysis of the partial genomic clone revealed a high conservation of the exons encoding the juxta-membrane (JM) and the 5' most protein tyrosine kinase domains. We have identified a segment of 22 amino acids conserved between the human and mouse JM domains; this segment may have a critical role in the function of the c-ros-encoded protein tyrosine kinase receptor.

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