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. 1992 Aug 15;48(8):768-73.
doi: 10.1007/BF02124300.

Regulation of rat renal (Na(+) + K+)-adenosine triphosphatase mRNA levels by corticosterone

L E Klein  1 , C S Lo
Affiliations

Regulation of rat renal (Na(+) + K+)-adenosine triphosphatase mRNA levels by corticosterone

L E Klein et al. Experientia. .

Abstract

We investigated the mechanisms for glucocorticoid regulation of rat renal NaK-ATPase activity. Our findings suggest that the magnitudes of corticosterone-induced increases in alpha 1 mRNA and beta 1 mRNA levels are similar in the kidney of the adult adrenalectomized rats. The results also suggest that corticosterone restores NaK-ATPase activity in adrenalectomized rats prior to any enhanced sodium delivery.

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