Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1992 Jul-Aug;47(4):374-80.

[New naphthalenic ligands of melatoninergic receptors]

[Article in French]
G Adam  1 , B Guardiola-Lemaitre, S Yous, D Lesieur, P Morgan, H E Howell, J Andrieux, D H Caignard, B Pfeiffer, P Renard
Affiliations
  • PMID: 1328595

[New naphthalenic ligands of melatoninergic receptors]

[Article in French]
G Adam et al. J Pharm Belg. 1992 Jul-Aug.

Abstract

Twenty three naphthalenic bio-isosteres of melatonin have been synthesized. The main structural variations concerned the acylamino substituents of the side chain and the alkoxy group on the 7-position of the naphthalene. Some of these compounds show greater affinity than melatonin itself for the melatonin receptor. The results of this study provide new informations on the structure affinity relationships and on the mode of interaction at the melatonin binding site.

PubMed Disclaimer

Publication types

LinkOut - more resources